Chunk #33 — Results — Changes in expression of genes that were altered by alcohol drinking and also significantly differed between alcohol-naïve P and NP rats

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Changes in gene expression within the ventral tegmental area following repeated excessive binge-like alcohol drinking by alcohol-preferring (P) rats.

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Among the 62 genes, 43 differed between the alcohol-naïve P and NP rats and changed toward NP expression levels as a result of binge drinking in the P rats (Table 6). There were 28 genes lower in the P than NP rats that were up-regulated in the ethanol group compared to the water group, and 15 genes higher in the VTA of the P than NP rats that were down-regulated with alcohol drinking.