Research is beginning to identify risk factors for suicidal behaviors. In the current analysis, we demonstrated that polygenic scores for suicide attempt, depression, and PTSD, and lower neurophysiological functioning were associated with suicide attempts among individuals with AD. Future work with larger and more diverse samples can examine additional risk factors, such as social and environmental conditions. Identifying robust predictive markers within an already high risk group may allow for earlier intervention and prevention from unnecessary loss of human life.