Using a method optimized to detect large anomalies (50 kb to whole chromosome), we identified at least one non-mosaic anomaly (i.e. large CNV) in 75% of all subjects, at least one clonal mosaic anomaly in 0.80%, and both types in 0.69%. The median size of all anomalies detected is 150 kb (Supplementary Fig. 5) and the mean number per subject is 1.5, with a range of 0 to 13. There were 514 mosaic anomalies in 404 of 50,222 subjects analyzed.
