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Chunk #32 — Discussion

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Brain expression quantitative trait locus and network analyses reveal downstream effects and putative drivers for brain-related diseases.
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We describe an integrated analysis of the effects of genetic variation on gene expression levels in the brain with a sufficient sample size to identify robust cis-eQTLs and cell-type ieQTLs to compare cis-eQTLs between ancestries and identify brain trans-eQTLs that emanate from SNPs that have been previously linked to brain-related diseases. We have released harmonized results of the individual datasets to help others determine the robustness of eQTL effects.