Short-term eCB mediated synaptic plasticity in the form of depolarization-induced suppression of excitation (DSE), has also been described in the LA (Kodirov et al., 2009). Lutz and co-workers found that 10 seconds of depolarization produced a slowly developing, low magnitude depression of EPSCs recorded from LA pyramidal neurons. DSE of sEPSCs was also observed in this study, both of which were mediated via activation of CB1 receptors (Kodirov et al., 2009).
