remission), and active treatment attrition (treatment efficacy). Additionally, TS/CTD was found to moderate treatment outcome in active comparison trials. The finding that CBT trials that had a greater incidence of co-occurring anxiety disorders exhibited larger treatment effects may suggest that OCD comorbid with other anxiety disorders could be driven by a more fear-based psychopathology which then leads to a more robust CBT response. The relationship between a greater number of CBT contact hours and larger treatment effects is consistent with psychosocial interventions for related disorders.[64; 65] Similarly, CBT trials that had higher treatment dropout rates were associated with lower therapeutic benefit. Taken together, these findings suggest that youth who persist in treatment and receive a full-course of CBT may likely experience optimal therapeutic benefit. While trials that emphasized ERP exhibited larger effects relative to CT, the difference was not statistically significant. Notably, the power to detect this statistical difference was largely constrained by the small number of trials that emphasized CT, as well as the possible overlap between “behavioral experiments” used in CT trials and “exposures” in ERP trials. Finally, the association between greater ES and a greater incidence of TS/CTD in active comparison trials is consistent with recent findings
