displayed so many nominally-significant results near the clustered positive results from the two NIDA samples. 2133 of the nominally-significant SNPs from the current nicotine dependent vs control comparison meet several criteria. They 1) lie near clusters of positive SNPs from both NIDA samples, 2) lie within annotated genes, 3) lie within genes that also supported by nominally-positive results from JGIDA methamphetamine abuser vs control comparisons and 4) lie within genes that are also supported by nominally-positive results from COGA alcohol dependent vs control comparisons. The Monte Carlo p value for the observed degree of convergence between the current and prior data is 0.018.
