reversed by 0.3 mg/kg rimonabant [Fig. 2, panel B; F(4,24)=15.67, P<0.05], a dose combination that also significantly suppressed responding compared to vehicle and to 30 mg/kg JZL184 alone [Fig. 2, panel D; F(4,24)=7.29, P<0.05]. Response rates were not significantly decreased (compared to vehicle) with THC or either enzyme inhibitor (Fig. 2, panels C and D).