consistent results for association with OD, CD or MD in several ethnic groups (Chen et al. 2002; Dahl et al. 2005; Nomura et al. 2006; Ray et al. 2005; Wei et al. 2011; Williams et al. 2007). An association between three SNPs (rs910080, rs910079 and rs2235749) in the 3′ UTR, and the haplotype CCT, with both CD and CD/AD, was reported in EAs, but not in AAs (Yuferov et al. 2009). Allele-specific gene expression of PDYN, using SNP rs910079 as a reporter, in postmortem human brains, showed lower expression for the C-allele in the caudate and nucleus accumbens. Total PDYN expression was also lower in carriers of the CCT haplotype (Yuferov et al. 2009).
