The prioritized SNP, rs17664708, was genotyped for a replication study in 2543 AAs and 2042 EAs (ethnicity verified or re-classified by STRUCTURE using 41 mostly short tandem repeat (STR) AIMs (20, 37). Genotyping was performed with a fluorogenic 5′ nuclease assay method (TaqMan technique), using the ABI 7900HT real time PCR system (ABI, Foster City, CA). The missing rate for genotyping was 0.03 in the replication sample. For genotyping quality control, 8% of samples were re-genotyped with 100% concordance.
