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Chunk #25 — Results — Examining Sensation Seeking and Social Support as Indirect Pathways Linking alc-GPS and Alcohol Use

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The associations between polygenic risk, sensation seeking, social support, and alcohol use in adulthood.
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The path model demonstrated excellent fit (χ2 = 24.02, df = 2, p < .001; CFI = .99, RMSEA = .06; SRMR = .01). Results from the path model are summarized in Table 2 and illustrated in Figure 2. Consistent with our expectation, alc-GPS was associated with sensation seeking at T1, which in turn was associated with alcohol use at T2. alc-GPS was associated with reduced family support, but was not significantly associated with friend support. Friend support, but not family support (p = .06), was significantly associated with lower alcohol use at T2. Alc-GPS remained significantly associated with alcohol use at T2, above and beyond covariates (age, sex, PC1-PC3), sensation seeking, and social support.