computerized version of the Diagnostic Interview Schedule to assess diagnostic status. In cases where a biological parent was not directly interviewed (21% of fathers and 4% of mothers in the current subsample), the reporting parent was used as the informant using the Family History Research Diagnostic Criteria (Andreasen, Endicott, Spitzer & Winokur, 1977). Thus, a lifetime diagnosis at the time of the baseline assessment was made based on DIS self-reports or Family History-Research Diagnostic Criteria spousal-reports.