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Chunk #38 — Discussion — Effects of age and sex on regional nodal properties

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Topological organization of functional brain networks in healthy children: differences in relation to age, sex, and intelligence.
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Significant sex-related differences in the regional nodal parameters were also found in various brain regions, which were primarily related to the default mode system (e.g., SFMmed.R), the language system (e.g., IFGtriang.L, REC.L, ORBinf.L, and PUT.L), and the vision system (e.g., bilateral LING and FFG). Our results were consistent with the notion that cognitive and emotional development differs between females and males, particularly in visuospatial, language, and emotion processing [73], [79], [80]. Interestingly, the identified brain regions involved in the language system were all from the left hemisphere, whereas those related to the visuospatial processing were from the right hemisphere. These findings supporting the notion that differences in laterality between males and females when processing language versus visuospatial information [81], [82].