number of hippocampal neurons expressing mTll1 were found in mice with increased neurogenesis, which is related to the stress response (31,37). Research on reptilian orthology of TLL1 isolated from turtle showed that the gene cleaves the precursor pro-brain-derived neurotrophic factor (proBDNF) into mature BDNF (38). The mature form of BDNF is involved in learning and memory and is very important in normal neural development.
