Chunk #9 — Introduction — The current study

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The CHRNA5/A3/B4 gene cluster and tobacco, alcohol, cannabis, inhalants and other substance use initiation: replication and new findings using mixture analyses.

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be possible to observe a class with an early age of initiation of alcohol and tobacco and a late first use of cannabis, versus a class with a reverse pattern of initiation. In the LCA models, SNPs were used to predict differences between classes.