Chunk #38 — 4. Discussion — 4.1. Aberrant FC in Individuals with AUD — 4.1.2. Hypoconnectivity across Anterior–Posterior and Interhemispheric Connections in AUD
found in abstinent AUD individuals [113]. Furthermore, diffusion tensor imaging (DTI) studies have reported widespread abnormalities in the white matter tracts of associative fibers [114,115] as well as interhemispheric fibers [6,116]. In sum, although these findings support the view that weaker anterior–posterior connectivity representing attentional and higher-cognitive processing can be a marker in addiction in general, more FC studies on AUD and related disorders are needed to elucidate distinct and shared neural mechanisms underlying AUD and other addictions.
