Since the publication of DrugBank 5.0, the number of drug–drug interactions has grown from 365 984 to 1 413 791, nearly a 300% increase. This large number of interactions is possible in part due to the newly developed ability to create interactions between drug categories and between an individual drug and drug category. However, these less specific category-based interactions are subservient to specific drug–drug interactions catalogued for any given pair of drugs, ensuring the most accurate information on drug–drug interactions is provided.
