paperKB
coga / coga-kb
Help
Sign in

Chunk #18 — MATERIALS, METHODS AND SAMPLES — Gene Expression Analysis — Statistical Analysis of Expression by rs1344706 Genotype

Source
Replication of association between schizophrenia and ZNF804A in the Irish Case-Control Study of Schizophrenia sample.
Embedded
yes

Text

We assessed sequence around SNP rs1344706 in the UCSC Genome Browser (http://genome.ucsc.edu). Based on evidence of conservation, we sought to identify transcription-factor bindingsites altered by the alternative rs1344706 alleles. A 53 bp sequencesurrounding rs1344706 (chr2:185,486,646-185,486,698) was analyzed using MatInspector v7.7.3.1 and SNPinspector v2.251 (http://www.genomatix.de/). In both cases the vertebrate transcription factor matrices and optimized matrix threshold were used to reduce the incidence of false-positives.