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Chunk #5 — Introduction

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Genome-wide association study of obsessive-compulsive disorder.
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The International OCD Foundation Genetic Collaborative (IOCDF-GC), consisting of more than 20 research groups, has performed a GWAS to search for common SNPs predisposing to OCD. We present our findings from an analysis of the genetic association between OCD and a genome-wide set of common SNPs among case-control and trio samples and their combined trio-case-control results. We also present analyses of top GWAS findings with respect to their biological function in OCD-related and other brain regions.