blood data because of its larger sample size (Supplementary Fig. 23). We repeated the SMR analysis using blood eQTL data from the Consortium for the Architecture of Gene Expression (CAGE; n = 2765)9 and observed similar results (Fig. 5b) although the power of CAGE was lower than that of eQTLGen (63 genes identified using CAGE versus 97 genes identified using eQTLGen).