increased by nearly 22% (Figure 1b).3 Recently, Vigo et al.4 compellingly argued that the global burden of mental illness is likely underestimated by more than one-third, suggesting that the effect of psychiatric disease may be even more dramatic than currently estimated. Finally, mental illness also leads to a significant economic impact estimated to be equivalent to the cost of cancer care.5 Serious mental illness was estimated to be associated with a loss of $193.2 billion in personal earnings across the United States.6
