Chunk #20 — Background — Details of data simulation — 2. Areas with LD/unique characteristics

Source

Construction of the model for the Genetic Analysis Workshop 14 simulated data: genotype-phenotype relationships, gene interaction, linkage, association, disequilibrium, and ascertainment effects for a complex phenotype.

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There is LD between the SNPs of the detailed map (markers named beginning with the letter "B" available from the web site described in the data description) in regions surrounding three of the four major disease loci. There is also LD in four regions that do not contain disease loci.