Chunk #51 — Background — Description of clinical characteristics of KPD and how the family data were collected and classified

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Construction of the model for the Genetic Analysis Workshop 14 simulated data: genotype-phenotype relationships, gene interaction, linkage, association, disequilibrium, and ascertainment effects for a complex phenotype.

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Because of these varied phenotypes, there has been much disagreement about how the disorder should be defined. Nosology for KPD falls into three different classifications; all three, or combinations thereof, have been used to diagnose KPD: