Chunk #11 — 3. Criteria for an animal model of alcoholism — 3.1. Neurobehavioral correlates with alcoholism

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Animal models for medications development targeting alcohol abuse using selectively bred rat lines: neurobiological and pharmacological validity.

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et al., 2002; Viken et al., 2003), heart rate (Finn and Justus, 1997; Peterson et al., 1996), and brain activity (Lukas et al., 1986; Sorbel et al., 1996; Trim et al., 2010) the stimulating effects of ethanol are not as readily seen in humans compared with rodents.