Data from 5053 directly interviewed FDRs of 176 child and adolescent and 899 adult OCD probands and 522 control probands (95 from children/adolescents and 427 from adult samples) were pooled for meta-analysis. The analyses combining pediatric and adult probands showed that FDRs of OCD probands had higher risks for definite OCD (OR = 7.18, 95% CI 4.13–12.47, p < 0.00001) than the FDRs of controls (Fig. 2).
