We have previously generated large array data sets that survey gene expression in different brain regions of the BXD strains. These data sets profile up to 71 members of the BXD family and have been used extensively for eQTL mapping. In this study, we used the Hippocampus Consortium M430v2 (June06) RMA as the primary mapping data set.29 Additional data sets from the whole brain, prefrontal cortex and cerebellum were used to verify the strong cis-effect for Per3 (see Table 2 of Mozhui et al.30 for an overview of these data sets). A detailed description of strain, sex, tissue preparation and microarray method, normalization and correction procedures for each individual data set is available at www.genenetwork.org.
