Our results also showed topographic differences of theta power across genotype during the loss condition (Fig. 4, panel A), with a gradual shift from a highly anteriorized topography of the AA genotype through a less anteriorized topography of the AG genotype to a weakly posteriorized topography of the GG phenotype. Similar results were seen in the ERP waveforms and topography across the genotype groups (see Fig. A1 in Appendix) but were less robust compared to the theta ERO findings, suggesting that time-frequency measures may be more useful to identify group differences. Previous studies have reported that ERO measures were better able to discriminate between alcoholics and controls and between high-risk offspring of alcoholics and low-risk offspring of controls (Jones et al., 2006b; Rangaswamy et al., 2007).
