We examined all the CpG sites (−93, −90, −60, −50, −25, −18,−14, −10, +12, +23, +27, and +84) that had a significant difference in methylation levels between cases and controls in any of the three ethnicities (Table 5; Nielsen et al. 2009). The level of methylation was significantly higher in the cases than in the controls (14.6% cases, 13.9% controls; P = 0.0457). When we did this test separately for each ethnicity, there was no significant difference between cases and controls.
