novel (10% ethanol) odor from familiar (own) odor [F(1, 34) = 14.9, p < .001, main effect of novelty] without differences between groups (Fig. 7C). In contrast, in B6 female mice their ability to uncover the “buried odor” of ethanol was dependent on treatment [F(1, 40) = 8.8, p < .01] and time [F(1, 40) = 11.3, p < .01]. Post-hoc analyses showed that females pretreated with LPS located the ethanol scent significantly faster but only on the first day of the experiment (p < .01) (Fig. 7D). Also, no differences between groups were found in their ability to locate the visible (with or without ethanol) target. No differences in ability to discriminate between novel (ethanol) or familiar (own) scents were found in female mice [F(1, 36) = 18.8, p < .001, main effect of novelty] (Fig. 7F). Thus, the increased alcohol consumption cannot be attributed to altered olfactory function.
