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Chunk #13 — Background

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Protocol for a collaborative meta-analysis of 5-HTTLPR, stress, and depression.
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4. Type of outcome . Some studies used a categorical measure of depression diagnosis (e.g. DSM-IV or the ICD-10) as an outcome, others used a symptom count as continuous outcome, and some used both. Such differences in outcome measures (e.g., continuous versus categorical) result in different assumptions and analytical approaches being used (see for a Discussion [36]).