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Chunk #29 — Discussion

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Polygenic signal for symptom dimensions and cognitive performance in patients with chronic schizophrenia.
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Literature also supports a polygenic basis for social cognition. Social cognition measured by emotion recognition was found to be associated with PRS in subjects between the ages of 8–21 with findings replicated in a sample of healthy adults (Germine et al., 2016). Of importance here, is that PRS was specifically associated with the speed of emotion recognition and not the ability to recognize emotion per se. Our study did not support a polygenic association and is likely due to measurement differences. Our social cognitive variable assessed for the ability to discriminate emotion and did not measure the speed, which could explain the lack of association.