With respect to alcoholism, in a study on alcoholics using an equal probability visual Go/NoGo task, Kamarajan, Porjesz (2004) reported lower delta and theta oscillatory activity at frontal regions, particularly during NoGo trials, in abstinent alcoholics compared to controls. The authors also found significantly lower ERO activity in delta, theta, and slow alpha (8-9 Hz) bands during the NoGo condition, as well as lower delta and theta activity during the Go condition in offspring of alcoholic parents (Kamarajan et al., 2006). Other than this study by Kamarajan, Porjesz (2006) on high-risk subjects, ERO studies have mainly examined slow waves such as delta and theta while evaluating performance during a Go/NoGo task. Therefore, considering the activation-inhibition dimension being examined in a Go/NoGo task, along with the previously reported literature regarding the functional significance of various frequency bands, it would be important to examine spectral power of delta, theta, and alpha frequency bands that are time-locked to the execution (Go) and suppression (NoGo) of a motor response as well as their patterns and topographical densities of relative appearances in the mental chronometry.
