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Chunk #34 — Discussion

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Genome-wide association study of lifetime cannabis use based on a large meta-analytic sample of 32 330 subjects from the International Cannabis Consortium.
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On the basis of our observations, the following recommendations for future studies can be made. We have identified four genes significantly associated with cannabis use, which are candidates for follow-up functional studies. In particular, the role of NCAM1 can be examined to determine the functional role of this gene, possibly in combination with other genes in the same gene cluster (NCAM1–TTC12–ANKK1–DRD2).