Genome-wide association studies (GWAS) have linked a large number of common genetic variants to various phenotypes. For most common phenotypes, high-powered meta-analyses have revealed tens to hundreds of single nucleotide polymorphisms (SNPs) with robust associations. However, deriving biological knowledge from these associations is often challenging[1,2]. Many genes function in multiple biological processes and it is typically not clear which of these processes is related to the phenotype in question.
