10−5 level which were smaller by a factor of two than the effect sizes presented in this study. A previous study of LIN28B (Widén et al., 2010, p. 778) showed opposite effects for sexes in two SNPs from about age 8 to early adolescence. A study by Sovio et al. (2009) found age (infancy compared to puberty) but no sex specific genotypic effects for a number of SNPs (Table 2 in Sovio et al. (2009)) for height velocity. More peripheral instances of age variation in genotypic effect were shown in Chorlian et al. (2013) where some CHRM2 SNPs were found to affect risk for the onset of alcohol dependence in adolescents and young adults only in those who became alcohol dependent under the age of 16 and in Hill et al. (2013), mentioned above.
