Since the inverse problem in itself is underdetermined, most solutions use a mathematical criteria to find the optimal result. This however leaves out any reliable biophysical and psychological constraints. LAURA takes this into consideration and incorporates biophysical laws in the minimum norm solutions (MN, WMN, LORETA and EPIFOCUS [38]) and the simulation showed that EPIFOCUS and LAURA outperform LORETA. This comparison was done by measuring the percentage of dipole localization error less than 2 grid points.
