which allows for a more comprehensive examination of the varying roles that social support could play in the relation between alc-GPS and alcohol use. We also considered social support from family and friends, allowing us to understand whether pathways of associations vary across sources of social support. Furthermore, we used the state of the science genome-wide polygenic score approach to characterize individuals’ genetic predispositions using results from a large GWAS study to capture the polygenic nature of the alcohol use phenotype. Finally, we used a large sample of adults with a wide age range, allowing us to examine potential age differences in the associations across emerging to middle adulthood.