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Chunk #13 — Results — Polygenic Association for EduYears-GPS and SUDs

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Sibling comparisons elucidate the associations between educational attainment polygenic scores and alcohol, nicotine and cannabis.
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We identified the P<0.30 threshold for AUDSX, P<0.20 for NDSX, and P<0.01 for CUDSX as the EduYears-GPS thresholds most strongly associated with each SUD criterion count. As shown in Table 2, higher EduYears-GPS was associated with lower SUD criteria. The EduYears-GPS accounted for 0.79%, 1.84%, and 0.30% of the variance in AUDSX, NDSX, and CUDSX, respectively.