Chunk #27 — Examples of Specific Environments that Could be Modeled Across Species: Early Alcohol Exposures and the Peer Environment — Early Alcohol Exposures
clear causal mechanism (perhaps because of increased sensitivity of the brain to alcohol or alcohol-related cues) or are an artifact of a common “third variable” associated with both early deviant behavior and the development of AUDs. Currently the data are ambiguous, with some evidence suggesting that the early alcohol drinking → AUD link is an spurious effect of correlated disinhibitory problems (Prescott & Kendler, 1999), some a true genotype x environment interaction effect (Agrawal et al., 2009) and it remains unclear whether common third-variable causation is a sufficient explanation (McGue & Iacono, 2008; Odgers et al., 2008).
