Strictly speaking, our results apply only to the UK Caucasian population, but we should expect similar results in other outbred populations of the same age. The HapMap data could be used to apply our methods to African and Asian populations, using a denser map of SNPs, but because of the small sample size we are not confident that the genomewide distribution of statistics from permutation samples is the same as would be applicable to a large sample. We therefore restricted our study to a large sample that has been used for a real genomewide association scan.
