of lactate is produced in a process known as the Cori cycle, in which lactate produced by glycolysis in exercising muscle is shuttled to the liver where it is converted back into glucose. Also in adipose tissue, glucose is metabolized to lactate, which can subsequently be transported to the liver. Alternatively, pyruvate produced in muscle by glycolytic oxidation of glucose can be converted to alanine via transamination (see Section 3.4). Alanine is exported from muscle tissue to liver, where it is reconverted to pyruvate and subsequently used in gluconeogenesis to produce glucose. The latter can be transported back to muscle in the glucose-alanine cycle.
