Measures comprising the domains significantly predicted by AD group were examined in regression follow-up regression analyses. When demographic and other substance use variables were held constant, AD group status was associated with: poorer performance on immediate and delayed recall of thematic units on the CMS Stories test (β = −.35, p = .017, and β = −.32, p =.037, respectively; Verbal Story Memory domain); more color-word errors on the SCWT (β = .50, p = .001; Self-Monitoring domain); and longer time to completion with the non-dominant hand on the GPT (β = .39, p = .018; Psychomotor Speed and Coordination domain). Overall, the regression models here demonstrated that, on these four dependent measures, alcohol use, other substance use, and the listed demographic variables together accounted for between 21% and 43% of variability in performance between AD and control participants. On these four dependent measures, the use of tobacco and other drugs was not significantly associated with performance. Age was, however, associated with number of SCWT color-word errors (i.e., older children made fewer errors); similarly, more years of education was associated with better performance on all four measures.