Chunk #29 — Methods — Comparison with existing methods

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Leveraging functional annotations in genetic risk prediction for human complex diseases.

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were tuned through cross-validation as we did for AnnoPred. Besides all these PRSs, we also compared AnnoPred with a evaluating method used in [5], which uses 1E-1, 1E-2,…, 1E-5 as p-value threshold to select SNPs and report the accuracy for the best performed threshold (S4 and S5 Tables).