stress and impulsivity. Individuals with the G allele may need to drink more alcohol to achieve the desired effects compared to AA subjects who experienced a higher subjective response to alcohol 4. One11 of the three studies that reported the A allele for the two SNPs in this study associated with alcohol-related measures, found the haplotype containing the A allele for both SNPs associated with alcoholism compared to controls but when the SNPs were analyzed independently, no association was observed. Our results may contribute to a better understanding of GABRA2 variation on Impulsiveness measures. The G allele of both SNPs and corresponding G-G haplotype was associated with a specific kind of Impulsiveness that assesses rash action in response to distress - with rashness indicating impulsive action along with later regret.
