Given expected error in location estimates (Atwood and Heard-Costa, 2003), our suggestive findings converge with numerous previous reports. Linkage peaks on chromosome 5, which are maximal for the younger sample (LOD 2.7) and enhanced through exclusion of the lowest alcohol users, are approximately 10–15cM from that reported for response to alcohol (Schuckit et al., 2001) and age of onset/harm avoidance/novelty seeking (Dick et al., 2002) and approximately 35cM from a region implicated in alcoholism (Hill et al., 2004).
