Chunk #51 — Methods — Identification of DMRs

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Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells.

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For the analysis of CG island reprogramming, the CG-DMRs were identified as for the Fig. 3 CG-DMRs (minimum enrichment 2-fold) but including the IMR90, ADS-adipose, ADS and FF differentiated cell lines in addition to the two ES cell and the five iPSC lines.