brain regions. Indeed, recent work has demonstrated a decrease in functional heterogeneity in right prefrontal cortex following ethanol administration (Volkow et al., 2008). A decrease in asymmetry has also been observed while inebriated patients participated in a verbal fluency task (Wendt and Risberg, 2001). In this case, the decrease in lateral activation of the left dorsolateral PFC, a region associated with language performance, correlated with decreased performance on the task. Another study examined the effects of acute EtOH on memory encoding that ordinarily depends upon activation of the right PFC (Soderlund et al., 2007). Again, ethanol administration decreased performance on the task, and this was associated with reduced bilateral PFC activation.
