Table 1 shows demographic, alcohol use and clinical measures for the TNAD and NAC groups. Both groups included subjects encompassing the entire range from 20 to 50 years; neither age nor years of education differed by group or gender. TNAD, on average, had a density of first degree relatives with alcohol problems that was 50% higher than NAC (F(1, 136) = 4.823, p = 0.030), but was markedly less than our previously reported results for long-term abstinent alcoholics (LTAA) (di Sclafani et al., 2008), about forty percent for LTAA vs. about twenty percent for TNAD (F(1, 119) = 21.080, p < 0.001, with group (LTAA vs. TNAD) accounting for 15 percent of the variance of family history density). As anticipated, alcohol consumption was dramatically greater in the TNAD vs. NAC, as these variables were associated with group selection criteria. TNAD drank over 12 times as much as NAC. We did not assess cigarette smoking in the study, but routinely do so in our current studies. As reported previously, there was also evidence of greater psychiatric comorbidity in the TNAD group, as reflected in higher Antisocial Personality Disorder and Depression symptom counts (di Sclafani et al., 2008).
