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Chunk #25 — Methods and Materials — Biometric Analyses

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The heritability of P300 amplitude in 18-year-olds is robust to adolescent alcohol use.
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Evidence that P300 is affected by varying levels of AAU is provided if the second Alcohol Exposure model fits the data better than the Endophenotype model. If the Alcohol Exposure model provides a significantly better fit, the affected model parameters can clarify some of the processes underlying the impact of AAU on P300 amplitude expression. Alternatively, evidence that AAU plays a minimal role in P300 amplitude expression is provided if the Alcohol Exposure model does not improve fit to the data.