Because the MarketScan data do not differentiate between patients who were receiving naltrexone for OUD as opposed to AUD, we further stratified between patients with existing AUD diagnoses at the time of OUD pharmacologic treatment initiation or during the 6 months preceding treatment initiation, and those without recent AUD diagnoses. AUD diagnoses were identified by insurance claims using ICD-9 and ICD-10 codes during any inpatient or outpatient encounter.
